Remanufactured for Canon CLI-251XLC Cyan Ink Cartridge (6449B001) – High-Yield | Castle Ink

Canon CLI-251XL Cyan (6449B001) at a glance: a high-yield cyan ink cartridge. Remanufactured: a genuine Canon CLI-251XL cartridge, cleaned, refilled and print-tested. Fits the Canon PIXMA MG5420–MG7520, MX722/MX922, iP7220/iP8720 and iX6820. Backed by a 1-year 100% satisfaction guarantee; orders by 4 PM ET (Mon–Fri) ship the same day from Long Island, NY.

Key Facts

What's in the Box

• 1 × Canon CLI-251XL Cyan (6449B001) remanufactured ink cartridge

Compatible Printers (15 models)

• Canon PIXMA iP7220 / iP8720
• Canon PIXMA iX6820
• Canon PIXMA MG5420 / MG5422 / MG5520 / MG5620
• Canon PIXMA MG6320 / MG6420 / MG6620
• Canon PIXMA MG7120 / MG7520
• Canon PIXMA MX722 / MX920 / MX922

Don't mix these up: PGI-250 (pigment black for text) and CLI-251 (dye colors and black) work together. The CLI-251 gray is used only by the MG6320, MG7120, MG7520 and iP8720. They are not the same as PGI-270/CLI-271 or PGI-225/CLI-226.

Not sure? Look up your exact model on our Find Ink by Printer page, or contact us and we'll confirm the right cartridge for you.

Printer guides: Canon PIXMA MX922 ink guide | Canon PIXMA MG5520 ink guide | Canon PIXMA MG6320 ink guide

Part Numbers & Also Known As

This cartridge replaces or is also searched for as: 6449B001, Canon 6449B001, Canon CLI-251XL cyan, CanonCLI-251XL cyan, CLI-251XL cyan ink, CLI-251XLC, CLI-251XL, CLI251XL, Canon 250 251 ink, MX922 ink, MG5520 ink

Chips, Printer Messages & Installation

Installing: with the printer on, open the cover and wait for the print head holder to stop. Press the tab on the empty tank and lift it out, remove the orange cap from the new tank, then press it down into the slot with the matching label until it clicks. The lamp on the tank lights when it is seated correctly.

Ink level messages: the printer may say the remaining ink level cannot be detected. Press and hold the Stop/Resume button for about 5 seconds to continue; the warning is disabled for that tank only.

Streaks or missing colors: run a nozzle check and cleaning from the maintenance menu. The print head stays in the printer, so let it rest between cleanings and run a deep cleaning only if needed.

Still stuck? See our guide to fixing a cartridge that isn't recognized or contact us and we'll make it right.

Remanufactured vs. Compatible vs. Original

Original (OEM) cartridges are new from the printer brand and cost the most. Remanufactured cartridges, like this one, start as genuine original shells (including the original chip) that are cleaned, refilled with high-quality ink and print-tested, so they fit and communicate like the original at a fraction of the price. Compatible cartridges are built new by a third party with their own chip. Castle Ink sells remanufactured inkjet cartridges and compatible (newly manufactured) toner.

Other Options for the Same Printers

• Canon CLI-251XLBK Black Ink Cartridge (6448B001)
• Canon CLI-251XLGY Gray Ink Cartridge (6452B001)
• Canon CLI-251XL Gray Ink Cartridge (CLI-251XLGY) (6452B001)
• Canon CLI-251XLBK Black Ink Cartridge (6448B001)
• Canon CLI-251XLM Magenta Ink Cartridge (6450B001)
• Canon CLI-251XLY Yellow Ink Cartridge (6451B001)

Frequently Asked Questions

Will this void my printer warranty?

No. Under the U.S. Magnuson-Moss Warranty Act, a manufacturer can't void your printer warranty just because you used a third-party or remanufactured supply. If a non-original supply directly caused damage, that specific repair might not be covered.

How long can I store it?

Store it sealed, at room temperature and out of direct sunlight, and use it within about 24 months for best results. Once opened, install it promptly.

When will my order ship?

Orders placed by 4 PM ET, Monday through Friday, ship the same business day from Long Island, NY, by USPS (2–5 business days). Expedited 1–2 day delivery is available at checkout, and shipping is free on orders over $50.