HP 21 & 22 Ink Cartridges – Black & Tri-Color

Castle Ink sells remanufactured HP 21 / 22 ink cartridges in every size HP makes: HP 21 black (C9351AN), HP 22 tri-color (C9352AN), a 21 black and 22 tri-color combo pack, and a 21 black MICR cartridge for check printing. They fit the HP DeskJet 3910, 3915, 3920, 3930, 3940, D1341, D1420, D1455, D1460, D2330, D2345, D2360, D2430, D2460, F340, F380, F2110, F2180, F2210, F2280, F4140, F4180, F4185 and F4190, the OfficeJet 4315 and J3680, and the PSC 1401, 1410 and 1417. Each cartridge is a remanufactured original HP shell, refilled and tested in the U.S. Orders placed by 4 PM ET ship the same business day, shipping is free over $50, and every cartridge is covered by our 1-year 100% satisfaction guarantee.

Firmware note: keep automatic firmware updates turned off on your printer so a future update can't block third-party cartridges. If the printer shows a “non-genuine ink” message, choose Continue or OK; printing is not blocked. Printing checks? Choose the MICR black version.

Need the details first? Read What ink does the DeskJet F4180 use?

4 products

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  • U.S. Remanufactured for HP 22 (C9352AN) Tri-Color Ink Cartridge
    $22.09
    $16.99
  • U.S. Remanufactured for HP 21 Black (C9351AN) Ink Cartridge
    $15.99
    $15.99
  • U.S. Remanufactured for HP 21 (C9351AN) Black MICR Ink Cartridges
    $53.29
    $40.99
  • Remanufactured for HP 21 Black and HP 22 Tri-Color Combo Pack Ink Cartridges
    $35.99
    $26.99

HP 21 / 22 Ink: Common Questions

What is the difference between the standard and XL HP 21 / 22 cartridges?

HP 21 black prints about 190 pages and HP 22 tri-color about 165; HP also made a 21XL black (C9351CN, about 475 pages) that fits the same slot. They share the same cartridge body and slot, so you can move between sizes freely.

Which printers use HP 21 / 22 ink?

HP DeskJet 3910, 3920, 3930, 3940, D1420, D1460, D2360, D2460, F340, F380, F2180, F2280, F4140, F4180, F4190, OfficeJet 4315, OfficeJet J3680, PSC 1410. Our Find Ink by Printer page has a guide for each model.

Will remanufactured HP 21 / 22 cartridges work in my printer?

Yes. These printers predate HP+ and HP's cartridge-blocking firmware, so a remanufactured cartridge installs and prints like an original. If the printer shows a non-genuine-ink message, choose OK or Continue. If a cartridge from us still isn't recognized, contact us and we'll replace or refund it under our 1-year guarantee.

Standard or XL: which should I buy?

XL in almost every case. The XL cartridges are the same physical size and fit the same slot, but hold more ink, so each printed page costs less. Standard cartridges only make sense if you print very rarely, since ink can dry out over long idle periods.

More help: What ink does the DeskJet F4180 use? · What ink does the DeskJet 3940 use? · What ink does the DeskJet F380 use? · All HP ink cartridges · Find Ink by Printer. Updated October 2026 by William Elward, founder of Castle Ink (in business since 2005).