What Ink Does the Epson Expression Premium XP-640 Use?

Quick answer: The Epson Expression Premium XP-640 uses Epson 410 ink in five separate cartridges: black, photo black, cyan, magenta and yellow. The high-yield Epson 410XL 5-pack gives the lowest cost per page.

Epson Expression Premium XP-640 Ink Cartridges at a Glance

The same Epson 410 / 410XL cartridges fit the Expression Premium XP-530, XP-630, XP-640, XP-6000, XP-6100, XP-7100, XP-830 and XP-970.

The Expression Premium XP-640 is a small-in-one photo printer with print, scan and copy, borderless photo printing and a CD/DVD printing tray. The extra photo black cartridge gives deeper blacks in photos.

Do not confuse Epson 410 with Epson 277 or Epson 212. They fit other Expression models and will not work in the XP-640.

Save on Epson 410 / 410XL

Castle Ink carries an Epson 410XL 5-pack with one of each color (black, photo black, cyan, magenta and yellow). Every cartridge is tested, backed by a 1-year guarantee, ships the same day when you order by 4 PM ET, and ships free on orders over $50.

Want to compare the real cost per page? Try our printer ink cost calculator.

How to Replace the Ink in the Epson Expression Premium XP-640

1. Turn the printer on and lift the scanner unit. The cartridge holder moves to the replacement position.
2. Shake the new cartridge gently four or five times, then unwrap it and remove the yellow tape (do not touch the green chip).
3. Squeeze the tab on the empty cartridge and lift it straight out.
4. Press the new cartridge down into its matching color slot until it clicks.
5. Lower the scanner unit and press the start or OK button if the screen asks. The printer charges the ink for a minute or two.

Troubleshooting Tips

"Ink cartridge cannot be recognized": Lift the scanner, press the cartridge down until it clicks, and check that the yellow tape is fully removed. If it still is not recognized, remove and reinstall all the cartridges, then restart the printer.

Streaks or missing lines: Run a nozzle check and head cleaning from the printer's Maintenance or Setup menu. Epson printheads are permanent, so cleaning is worth trying two or three times, letting the printer rest a few minutes between cycles.

Firmware updates: Some Epson firmware updates have blocked third-party cartridges. Turn off automatic firmware updates in the printer's settings or Epson Connect, and see printer firmware updates and third-party ink.

Official Epson Resources

• Epson Support
• Epson ink finder

Bottom Line

The Epson Expression Premium XP-640 runs on five Epson 410 cartridges. The 410XL set covers every slot and lowers the cost per page.

Written and reviewed by William Elward — Founder of Castle Ink, 20+ years in the printer & imaging supplies industry. Updated October 2026.

Frequently Asked Questions

How many ink cartridges does the XP-640 use?
Five: Epson 410 black, photo black, cyan, magenta and yellow.

What is the photo black cartridge for?
The printer uses photo black for photos on glossy paper and the regular black for text on plain paper. Both must be installed.

Can I mix 410 and 410XL cartridges?
Yes. They fit the same slots.

Does using third-party ink void my Epson warranty?
No. The U.S. Magnuson-Moss Warranty Act stops Epson from voiding your warranty just because you used third-party ink.

Shop Ink at Castle Ink

Find the right cartridge for the Epson Expression Premium XP-640 and every other printer we cover on the Find Ink by Printer page, browse all Epson ink cartridges, or work through a fault at our printer troubleshooting center.

Looking for a new printer? Epson Expression Premium printers on Amazon — as an Amazon Associate we earn from qualifying purchases.

See also: how to install Epson ink | Epson printer not printing | ink cartridge not recognized