What Ink Does the HP DeskJet F4280 Use?
Last Updated:Quick answer: The HP DeskJet F4280 all-in-one uses two HP 60 cartridges: one black and one tri-color. The high-yield HP 60XL versions fit too. Castle Ink stocks remanufactured 60XL Black, 60XL Tri-color and a 60XL 2-pack.
HP 300 is the European version of this cartridge and won't work in a U.S. F4280. The F4280 takes the same ink as the DeskJet F4480, Photosmart D110 and Photosmart C4680.
CastleScore · October 2026
69/100 — Situational
HP DeskJet F4280
| Pillar (weight) | Score | What it is based on |
|---|---|---|
| Owner ratings (28%) | — | No retailer rating with enough reviews to use. |
| Expert reviews (18%) | — | No published numeric expert score we could verify. |
| Cost per page (24%) | 85 | About 4.3¢ per page blended (black + color) with our remanufactured 60XL (600 / 440 pages). |
| Reliability (13%) | 78 | Most-reported problems: no current Windows 10/11 driver from HP; new HP 60 cartridges not recognized or failing alignment |
| Features (12%) | 50 | Print, copy, scan over USB. No Wi-Fi, no document feeder, no auto two-sided printing, no fax, no touchscreen. |
| Value (5%) | 78 | Running cost and owner satisfaction |
Limited data: We could not find enough owner ratings or published expert scores for this printer, so those weights are spread across the other pillars. With neither owner ratings nor a published expert score, we cap its CastleScore at 69 (Situational) under our methodology.
Discontinued. HP launched the F4280 in 2008 and now treats it as obsolete, but HP 60 and 60XL cartridges are still easy to find.
CastleScore is Castle Ink’s own editorial rating, built from retailer star ratings, expert reviews, real cost per page and owner complaint patterns, checked October 14, 2026. It is not a customer review. See every ranked printer or how the score works.
The cartridges, pictured
HP 60XL 2-packBlack + Tri-color
HP 60XL BlackCC641WN · ~600 pages
HP 60XL Tri-colorCC644WN · ~440 pages
HP 60XL 2-pack
HP 60XL Black
HP 60XL Tri-colorOur own remanufactured cartridges, photographed in-house.
What Ink Cartridges Does the HP DeskJet F4280 Take?
| Cartridge | HP part no. | Approx. yield | Castle Ink option |
|---|---|---|---|
| HP 60 Black | CC640WN | ~200 pages | — |
| HP 60 Tri-color | CC643WN | ~165 pages | — |
| HP 60XL Black | CC641WN | ~600 pages | Remanufactured 60XL Black |
| HP 60XL Tri-color | CC644WN | ~440 pages | Remanufactured 60XL Tri-color |
Some retailers list the 60XL tri-color at about 160 pages; HP rates it at 440. The F4280 predates HP's dynamic security and HP+, so it isn't locked to HP-branded ink.
Is HP 60XL Worth It?
Yes, by a wide margin. On October 14, 2026, Staples listed Original HP 60 black at $32.99 and 60 tri-color at $42.99, and Original 60XL black at $83.99 (about 14¢ a page). Our remanufactured 60XL black is $20.95 (about 3.5¢ a page) and 60XL tri-color $23.95 (about 5.4¢ a page), or $43.95 for the 2-pack.
How Do I Replace the Ink in the HP DeskJet F4280?
- Turn the printer on and open the cartridge door. Wait for the carriage to move to the center and stop.
- Press down on the old cartridge to release it and pull it toward you.
- Remove the new cartridge from its package and pull off the plastic tape by its pink tab. Don't touch the copper contacts or nozzles.
- Slide the cartridge into its slot, contacts first, and push until it snaps in.
- Close the door and print the alignment page when prompted, then place it on the scanner glass to finish aligning.
Which Other Printers Use HP 60?
The DeskJet F4480, DeskJet D1660, D2530, D2545, D2560, D2660 and D2680, the ENVY 110 and 114, and the Photosmart C4680, C4780, C4795 and D110.
What DeskJet F4280 owners ask
These are the questions that come up most for this printer in HP's support community and owner reviews, answered in our words.
Does the F4280 work with Windows 10 or 11?
HP treats the F4280 as obsolete and no longer offers a full software package. Windows' built-in driver often prints once the printer is connected by USB and added through Settings, but scanning features may be limited.
Does it have Wi-Fi?
No. It connects by USB only.
A new cartridge won't align or the black won't print. What should I do?
Remove the cartridge, make sure the tape is fully off, wipe the copper contacts with a dry lint-free cloth and reinstall it. Then run the printer's cleaning and alignment from the HP software or control panel.
Should I buy HP 60 or HP 300?
HP 60 in the U.S. HP 300 is the European version and is region-locked.
DeskJet F4280 quirks worth knowing
- HP launched it in 2008; it is long out of production.
- HP rated it at up to 26 pages a minute in black and 20 in color in draft mode; normal-quality pages are much slower.
- It prints, copies and scans; there's no fax, no document feeder and no automatic two-sided printing.
- The input tray holds 80 sheets, and HP rated it for up to 3,000 pages a month.
Frequently Asked Questions
What ink does the HP DeskJet F4280 use?
HP 60 or HP 60XL: one black and one tri-color cartridge.
Can I use HP 60XL in the F4280?
Yes. HP 60XL fits the same slots and prints about three times as many black pages.
Does HP 61 fit the DeskJet F4280?
No. HP 61 is a different cartridge for printers like the DeskJet 1000 and 2540. The F4280 takes HP 60.
Other printers that use HP 60
HP DeskJet F4480 · HP Photosmart D110 · HP Photosmart C4680
More HP ink guides: HP OfficeJet 3830 · HP Envy 5000 · HP OfficeJet Pro 8610 · find any printer
Replacing it? Our highest-rated alternatives
- Epson EcoTank ET-2980 (cheapest to run) — CastleScore 90
- HP Color LaserJet Pro 3201dw (laser) — CastleScore 82
- HP OfficeJet Pro 9125e — CastleScore 79
Sources
Ratings and prices were checked on October 14, 2026 and will change over time.
Need replacement HP ink cartridges? Shop HP ink cartridges at Castle Ink. Remanufactured, up to 70% less than OEM, and shipped the same day when you order by 4 PM ET.