What Ink Does the HP DeskJet F4180 Use?
Last Updated:Quick answer: The HP DeskJet F4180 uses two cartridges: an HP 21 black and an HP 22 tri-color. The high-yield HP 21XL and 22XL fit too. Castle Ink stocks remanufactured HP 21 Black, HP 22 Tri-color and a 21 + 22 combo pack.
It shares HP 21 and 22 with a long list of 2000s DeskJets, including the F2180, F4135, F4140 and D1360. Don't confuse it with the DeskJet F4280, which takes HP 60. Staples and some ink sellers also list the larger HP 57 tri-color and HP 58 photo for the F4180, but HP's own spec sheet lists only HP 21 and 22.
CastleScore · October 2026
67/100 — Situational
HP DeskJet F4180
| Pillar (weight) | Score | What it is based on |
|---|---|---|
| Owner ratings (28%) | — | No retailer rating with enough reviews to use. |
| Expert reviews (18%) | 65 | Computerwoche (Germany) 65/100, March 2008 |
| Cost per page (24%) | 74 | About 7.5¢ per page blended (black + color) with our remanufactured HP 21 black (190 pages) and HP 22 tri-color (165 pages). |
| Reliability (13%) | 80 | Most-reported problems: blinking cartridge and resume lights; refilled cartridges not recognized or showing empty; carriage jams |
| Features (12%) | 40 | Print, copy, scan over USB. No display, no Wi-Fi, no document feeder, no auto two-sided printing, no fax. |
| Value (5%) | 72 | Running cost and owner satisfaction |
Limited data: We could not find enough owner ratings for this printer, so that weight is spread across the other pillars.
Discontinued. HP launched the DeskJet F4180 in April 2007 at $79. It now turns up only used, but HP 21 and 22 cartridges are still sold.
CastleScore is Castle Ink’s own editorial rating, built from retailer star ratings, expert reviews, real cost per page and owner complaint patterns, checked October 15, 2026. It is not a customer review. See every ranked printer or how the score works.
The cartridges, pictured
HP 21 + 22 comboBlack + Tri-color
HP 21 BlackC9351AN · ~190 pages
HP 22 Tri-colorC9352AN · ~165 pages
HP 21 + 22 combo
HP 21 Black
HP 22 Tri-colorOur own remanufactured cartridges, photographed in-house.
What Ink Cartridges Does the HP DeskJet F4180 Take?
| Cartridge | HP part no. | Approx. yield | Castle Ink option |
|---|---|---|---|
| HP 21 Black | C9351AN | ~190 pages | Remanufactured HP 21 Black |
| HP 21XL Black | See note | ~475 pages | — |
| HP 22 Tri-color | C9352AN | ~165 pages | Remanufactured HP 22 Tri-color |
| HP 22XL Tri-color | See note | ~415 pages | — |
| HP 21/22 Combo pack | C9509FN | ~190 / 165 pages | Remanufactured 21 + 22 combo |
We couldn't confirm the U.S. part numbers for HP 21XL and 22XL; in Europe they're sold as C9351CE and C9352CE. HP also sold an HP 21 economy black, B3B18AN, rated at about 180 pages, but Staples showed it out of stock.
Is HP 21XL Worth It?
If you can find it at a fair price. The XL cartridges hold about two and a half times as many pages, but we couldn't find a current listing for them. On October 15, 2026, Staples listed HP's standard 21 black at $31.89 (about 16.8¢ a page) and the 22 tri-color at $48.99 (about 29.7¢ a page). Our remanufactured HP 21 black is $11.99 (about 6.3¢ a page) and the HP 22 tri-color $16.99, or $26.99 for the combo pack.
How Do I Replace the Ink in the HP DeskJet F4180?
- Turn the printer on, lift the cartridge door and wait for the carriage to move to the center and go quiet.
- Push the old cartridge down gently and pull it toward you. Tri-color goes on the left, black on the right.
- Unpack the new cartridge and pull the pink tab to remove the nozzle tape. Don't touch the copper contacts.
- Slide the cartridge forward into its slot, contacts toward the back, until it snaps in.
- Close the door. When the alignment page prints, place it face down on the glass and press the Scan button.
Which Other Printers Use HP 21 and 22?
The DeskJet F2180, F2210, F2240, F2280, F4135, F4140, F335, F340, F350 and F380; the DeskJet D1311, D1360, D1420, D1455, D1520, D1560, D2330, D2360, D2430 and D2460; the DeskJet 3910, 3915, 3930 and 3940; the OfficeJet 4315, J3640 and J3680; the PSC 1410; and the HP Fax 1250.
What DeskJet F4180 owners ask
These are the questions that come up most for this printer in HP's support community and owner reviews, answered in our words.
Why are the lights blinking?
Blinking lights usually mean a cartridge problem or a paper jam. Clear any jam, reseat or replace the cartridge the printer flags, and turn it off and on again.
It won't recognize a refilled cartridge.
Clean the copper contacts with a lint-free cloth and reseat the cartridge. Refilled HP 21 and 22 cartridges often keep reporting low or empty.
Does it have a screen or Wi-Fi?
No. It has buttons and lights only and connects by USB.
Why is the ink so expensive per page?
Standard HP 21 and 22 cartridges only print about 190 and 165 pages. XL or remanufactured cartridges bring the cost down.
DeskJet F4180 quirks worth knowing
- HP claimed up to 20 pages a minute in black in draft mode. Computerwoche called it slow and expensive to run.
- The scanner lid comes off so you can copy or scan thick books.
- The input tray holds 100 sheets, and HP rates it for up to 500 pages a month.
- It prints borderless 4x6 photos on tear-off strip paper.
Frequently Asked Questions
What ink does the HP DeskJet F4180 use?
HP 21 black and HP 22 tri-color, or HP 21XL and 22XL.
Does the F4180 use the same ink as the F4280?
No. The F4280 takes HP 60 cartridges.
Can it fax or scan a stack of pages?
No. There's no fax and no document feeder; scanning is flatbed only.
More HP ink guides: HP OfficeJet 3830 · HP Envy 5000 · HP OfficeJet Pro 8610 · find any printer
Replacing it? Our highest-rated alternatives
- Epson EcoTank ET-2980 (cheapest to run) — CastleScore 90
- HP Color LaserJet Pro 3201dw (laser) — CastleScore 82
- HP OfficeJet Pro 9125e — CastleScore 79
Sources
Ratings and prices were checked on October 15, 2026 and will change over time.
Need replacement HP ink cartridges? Shop HP ink cartridges at Castle Ink. Remanufactured, up to 70% less than OEM, and shipped the same day when you order by 4 PM ET.