Save 10% on your first order with code WELCOME10 →

Canon PIXMA TS6220 Ink: PGI-280 / CLI-281 XXL Cartridges | Castle Ink

The Canon PIXMA TS6220 wireless all-in-one printer uses Canon PGI-280 pigment black and CLI-281 dye-based color ink cartridges. The TS6220 is a five-cartridge configuration (PGBK, BK, C, M, Y) with XL and XXL high-yield options for better value.

Ink Cartridges at a Glance

Cartridge Color Approx. Yield
PGI-280 Pigment Black ~200 pages
PGI-280 XL Pigment Black ~400 pages
PGI-280 XXL Pigment Black ~600 pages
CLI-281 BK / C / M / Y ~236 pages
CLI-281 XL BK / C / M / Y ~466 pages
CLI-281 XXL BK / C / M / Y ~810 pages

The PGI-280 / CLI-281 cartridge family is also used by the Canon PIXMA TS6120, TS6320, TS8120, TS8220, TS8320, TS9120, TR7520, TR8520, and TR8620 series printers.

Save on PGI-280 / CLI-281 Ink

Castle Ink offers premium compatible PGI-280 and CLI-281 cartridges at up to 70% off Canon retail prices, with a full satisfaction warranty and free shipping on qualifying orders.

How to Replace Ink in the Canon PIXMA TS6220

  1. Power on the printer and open the front cover; the print head will move to center.
  2. Press the tab on the empty cartridge and lift it out of the print head.
  3. Remove the new cartridge from packaging and pull off the orange protective cap.
  4. Insert the new cartridge into the matching color slot and push down until it clicks.
  5. Close the front cover and wait for the printer to initialize.

Troubleshooting Tips

Cartridge not recognized: Remove the cartridge, wipe the gold contacts with a dry lint-free cloth, and reinsert firmly.

Streaky or faded prints: Run Print Head Cleaning from the TS6220's Maintenance menu on the touchscreen.

Misaligned colors: Run Print Head Alignment using plain paper to restore output quality.

Low ink warnings: Compatible cartridges may display ink-level warnings; printing continues normally.

Official Canon Resources

Canon PIXMA TS6220 Support · Canon Genuine Ink

Bottom Line

The Canon PIXMA TS6220 uses PGI-280 pigment black and CLI-281 dye-based color cartridges in standard, XL, and XXL sizes. Castle Ink compatibles deliver vibrant prints at a fraction of OEM cost — shop PGI-280 / CLI-281 ink now.

Frequently Asked Questions

Q: How many cartridges does the TS6220 use? Five — one PGI-280 pigment black plus four CLI-281 (BK, C, M, Y).

Q: Does the TS6220 have a Photo Blue cartridge? No — only the TS8120/8220/8320 and TS9120 use the 6th Photo Blue cartridge.

Q: What's the best size for high-volume printing? XXL high-yield offers the lowest cost per page.

Q: Are Castle Ink compatibles safe? Yes, engineered to OEM specs and backed by a satisfaction warranty.

Q: Can I mix XL with standard? Yes, you can mix any combination of standard, XL, and XXL cartridges.

— William Elward, Castle Ink

Written and reviewed by — Founder of Castle Ink, 20+ years in the printer & imaging supplies industry.